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1.
Med Clin (Barc) ; 2024 Apr 16.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-38632033

RESUMO

BACKGORUND AND OBJECTIVE: Royal Decree 888/2022 establishes that the evaluation of disability situations is carried out by multiprofessional teams responsible for assessing and recognizing the degree of disability. The participation of professionals in the healthcare and social fields can be valuable in providing reports from which the necessary data for the proper assessment of disability can be obtained, with the ultimate goal of providing comprehensive assistance to people with disabilities. MATERIALS AND METHODS: An analysis and summary of Royal Decree 888/2022, which has recently come into effect, is performed, focusing on the most relevant aspects for professionals in the healthcare and social fields. RESULTS: The recognition and classification of the degree of disability are the responsibility of the autonomous communities, and the assessments are issued by multiprofessional teams. To do this, four components are evaluated using the criteria outlined in the annexes of the Royal Decree itself. Each criterion generates a score that is combined to obtain a single score, the Final Disability Degree of the Person. CONCLUSIONS: The pathology that causes the disability must have been previously diagnosed by the Healthcare System and considered permanent. Its evaluation is based on the evidence of objective clinical findings that are documented and supported by clinical reports. For this reason, it is important to maintain an accurate medical history, document reviews, and provide all relevant evidence.

2.
PLoS One ; 18(3): e0283758, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36996121

RESUMO

BACKGROUND: Despite being a new entity, there is a large amount of information on the characteristics of SARS-CoV-2 infection and the symptoms of the acute phase; however, there are still many unknowns about the clinical features and pathophysiology of post-COVID syndrome. Refractory chronic cough is one of the most prevalent symptoms and carries both a medical problem and a social stigma. Many recent studies have highlighted the role of SARS-CoV-2 neurotropism, but no studies have demonstrated vagus nerve neuropathy as a cause of persistent chronic cough or other COVID-19 long-term effects. OBJECTIVE: The main objective was to assess the involvement of the vagus nerve neuropathy as a cause of chronic cough and other post-COVID syndrome symptoms. MATERIAL AND METHODS: This was a single-center observational study with prospective clinical data collected from 38 patients with chronic cough and post-COVID-19 syndrome. Clinical characteristics and laryngeal electromyographic findings were analyzed. RESULTS: Clinical data from 38 patients with chronic cough after 12 weeks of the acute phase of COVID-19 infection were analyzed. Of these patients, 81.6% suffered from other post-COVID conditions and, 73.6% reported fluctuating evolution of symptoms. Laryngeal electromyography (LEMG) of the thyroarytenoid (TA) muscles and cricothyroid (CT) muscles was pathological in 76.3% of the patients. Of the patients with abnormal LEMG, chronic denervation was the most frequent finding (82.8%), 10.3% presented acute denervation signs, and 6.9% presented myopathic pattern in LEMG. CONCLUSIONS: LEMG studies suggest the existence of postviral vagus nerve neuropathy after SARS-CoV-2 infection that could explain chronic cough in post-COVID syndrome.


Assuntos
COVID-19 , Doenças do Sistema Nervoso Periférico , Humanos , Eletromiografia , Tosse , Estudos Prospectivos , Síndrome Pós-COVID-19 Aguda , COVID-19/complicações , SARS-CoV-2 , Nervo Vago , Músculos Laríngeos , Doença Crônica
3.
Artigo em Inglês | MEDLINE | ID: mdl-36709799

RESUMO

BACKGROUND AND AIM: Although sensorineural hearing loss may have different aetiologies, we focused on autoimmune hearing loss since it may be reversible with corticosteroid therapy; this entity is sometimes associated with systemic autoimmune diseases. Hashimoto's thyroiditis or chronic autoimmune thyroiditis shows antibodies and may be harmful to hearing thresholds regardless of hypothyroidism effect. To date this effect has not been sufficiently studied and never with extended high frequencies. The aim of this work is to study by age groups whether hearing thresholds in the human auditory range (128-20,000Hz) are affected in Hashimoto's disease. MATERIALS AND METHODS: Two groups of 128 patients affected by Hashimoto's thyroiditis were included. First group: patients with pathological antithyroid antibodies who do not need L-thyroxine treatment. Second group: patients controlled with L-thyroxine substitutive treatment. Audiometric threshold study comparing between the groups of patients and a group of 209 controls was performed. All patients underwent complete otorhinolaryngological examination, antithyroid antibodies, TSH, T3 and T4 blood levels, tympanometry, conventional pure-tone audiometry, and extended-high-frequency audiometry. RESULTS: All patients were women. Both groups showed worst audiometric thresholds than the control group; both study groups showed worse hearing than controls, this difference was statistically significant in all frequencies. In the 8-20kHz frequency range, this difference was more than 10dB, and in the 9-16kHz and 20kHz range this difference was more than 20dB. When separated by age groups, in younger subjects (20-29 years) these differences were found in all frequencies, except for conversational frequencies (500-4,000Hz); between 30 and 49 years the difference is statistically significant in all frequencies; and from 50 to 69 years differences are found, especially in the conversational frequencies. CONCLUSIONS: This first work studying the human auditory range in the chronic autoimmune thyroiditis or Hashimoto's thyroiditis confirms that hearing loss related to the autoimmune disorder predominates at extended-high-frequencies initially. But ends up involving all frequencies in pure-tone conventional audiometry, then it may be detected in routine clinical tests. These results support the role of extended-high-frequencies audiometry to diagnose subclinical hearing loss in patients affected by Hashimoto's thyroiditis.


Assuntos
Doença de Hashimoto , Perda Auditiva , Tireoidite Autoimune , Humanos , Feminino , Adulto Jovem , Adulto , Masculino , Tireoidite Autoimune/complicações , Doença de Hashimoto/complicações , Tiroxina/uso terapêutico , Perda Auditiva/complicações , Audiometria de Tons Puros
4.
Acta otorrinolaringol. esp ; 74(1): 50-58, enero 2023. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-213930

RESUMO

Antecedentes y objetivo: Hay muchas causas de hipoacusia neurosensorial, entre las que tiene especial interés la patología autoinmune del oído interno por su posible reversibilidad con tratamiento esteroideo, a veces asociada a enfermedades sistémicas autoinmunes. La tiroiditis crónica autoinmune o de Hashimoto (TA) presenta anticuerpos que podrían afectar al oído interno independientemente del hipotiroidismo, efecto que no ha sido suficientemente estudiado y nunca mediante audiometría con extensión en altas frecuencias.El objetivo de este trabajo es estudiar si existe afectación de los umbrales auditivos en pacientes de TA, sin hipotiroidismo, en la totalidad del espectro auditivo humano (128 Hz – 20 kHz) distribuido por grupos de edad.Materiales y métodosSe han seleccionado 128 pacientes divididos en dos grupos. El primer grupo de pacientes presenta anticuerpos antitiroideos elevados sin necesitar tratamiento sustitutivo con tiroxina. El segundo grupo con tratamiento sustitutivo con tiroxina, bien controlados. Se comparan con el grupo control (GC) de 209 pacientes. En todos se realizó historia clínica, exploración otológica, estudio de niveles de anticuerpos antitiroideos, TSH (thyroid-stimulating hormone), T3 y T4 libres, timpanograma, estudio audiométrico convencional y con extensión en altas frecuencias.ResultadosTodos los pacientes fueron mujeres. Ambos grupos mostraron peor audición que los controles, siendo la diferencia estadísticamente significativa en todas las frecuencias; en el rango de frecuencias de 8 – 20 kHz con una diferencia de más de 10 dB, y en los rangos de 9-16 kHz y de 20 kHz de más de 20 dB. (AU)


Background and aim: Although sensorineural hearing loss may have different aetiologies, we focused on autoimmune hearing loss since it may be reversible with corticosteroid therapy; this entity is sometimes associated with systemic autoimmune diseases. Hashimoto's thyroiditis or chronic autoimmune thyroiditis shows antibodies and may be harmful to hearing thresholds regardless of hypothyroidism effect. To date this effect has not been sufficiently studied and never with extended high frequencies. The aim of this work is to study by age groups whether hearing thresholds in the human auditory range (128 to 20.000 Hz) are affected in Hashimoto's disease.Materials and methodsTwo groups of 128 patients affected by Hashimoto's thyroiditis were included. First group: patients with pathological antithyroid antibodies who do not need L-thyroxine treatment. Second group: patients controlled with L-thyroxine substitutive treatment. Audiometric threshold study comparing between the groups of patients and a group of 209 controls was performed. All patients underwent complete otorhinolaryngological examination, antithyroid antibodies, TSH, T3 and T4 blood levels, tympanometry, conventional pure-tone audiometry, and extended-high-frequency audiometry.ResultsAll patients were women. Both groups showed worst audiometric thresholds than the control group; both study groups showed worse hearing than controls, this difference was statistically significant in all frequencies. In the 8-20 kHz frequency range this difference was more than 10 dB, and in the 9-16 kHz and 20 kHz range this difference was more than 20 dB. When separated by age groups, in younger subjects (20-29 years) these differences were found in all frequencies, except for conversational frequencies (500 - 4,000 Hz); between 30 and 49 years the difference is statistically significant in all frequencies; and from 50 to 69 years differences are found, especially in the conversational frequencies. (AU)


Assuntos
Tireoidite Autoimune , Perda Auditiva , Doença de Hashimoto , Orelha Interna , Anticorpos
5.
Acta otorrinolaringol. esp ; 71(3): 175-280, mayo-jun. 2020. tab, graf
Artigo em Inglês | IBECS | ID: ibc-192633

RESUMO

OBJECTIVE: Presbycusis or age-related hearing loss is a bilaterally symmetric sensorineural hearing loss associated exclusively with age, excluding any other causes of hearing loss. Presbycusis is very relevant because of its high prevalence, and its consequences (e.g., alterations in communication, social isolation, depression, dementia), and the economic impact. This paper reports the first attempt to estimate the prevalence of presbycusis in an otologically normal population, i.e., without previous ear disease, exposure to noise, or potentially ototoxic substances, or familial hearing loss. METHODS: A total of 4290 subjects from 5 to 90 years old were included in the study. RESULTS: No statistically significant differences were found between right and left ear, nor between males and females, in any of the age groups. Presbycusis was detected over 60 years following the WHO classification; although the results vary depending on the classification used. Moderate hearing loss (≥ 41 dB) was detected in the population over 72 years. None of the subjects had severe or profound hearing impairment. The prevalence of presbycusis increased with age, being 100% in individuals aged 80 years and older. The prevalence of presbycusis is highly variable depending on the pure-tone averaged frequencies and the classification system used; therefore, a common classification system should be used. CONCLUSIONS: An otologically normal population is needed to establish the prevalence of presbycusis as in non-screened populations it is the hearing level including all types of hearing loss that is measured, but not presbycusis itself


ANTECEDENTES Y OBJETIVO: La presbiacusia o pérdida auditiva relacionada con la edad, es una hipoacusia neurosensorial bilateral y simétrica asociada exclusivamente a la edad. La presbiacusia es muy relevante debido a su alta prevalencia y sus consecuencias (alteraciones en la comunicación, aislamiento social, depresión, demencia) y el impacto económico. Este es el primer trabajo que aporta datos sobre la prevalencia de la presbiacusia en una población otológicamente normal, es decir, sin enfermedad auditiva previa, exposición a ruido o sustancias potencialmente ototóxicas o pérdida de audición familiar. MATERIAL Y MÉTODOS: Un total de 4.290 sujetos de 5 a 90 años de edad fueron incluidos en el estudio. RESULTADOS: No se encontraron diferencias entre el oído derecho y el izquierdo, ni entre varones y mujeres. La presbiacusia se detectó a partir de los 60 años siguiendo la clasificación de la OMS, aunque los resultados varían dependiendo de la clasificación utilizada. Se detectó hipoacusia moderada (≥ 41dB) en la población mayor de 72 años. Ninguno de los sujetos tenía hipoacusia grave o profunda. La prevalencia de presbiacusia aumentó con la edad, siendo del 100% en individuos de 80 años o más. La prevalencia de la presbiacusia es altamente variable dependiendo de las frecuencias promediadas y del sistema de clasificación utilizado; por lo tanto, debería utilizarse un sistema de clasificación común. CONCLUSIONES: Para establecer la prevalencia de la presbiacusia se necesita una población otológicamente normal ya que, si la población no está cribada, lo que se mide es la hipoacusia que incluye todos los tipos de pérdida auditiva, pero no la presbiacusia de forma aislada


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Presbiacusia/epidemiologia , Presbiacusia/classificação , Voluntários Saudáveis/estatística & dados numéricos , Audiometria , Análise de Variância , Disfunção Cognitiva/fisiopatologia
6.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31506162

RESUMO

OBJECTIVE: Presbycusis or age-related hearing loss is a bilaterally symmetric sensorineural hearing loss associated exclusively with age, excluding any other causes of hearing loss. Presbycusis is very relevant because of its high prevalence, and its consequences (e.g., alterations in communication, social isolation, depression, dementia), and the economic impact. This paper reports the first attempt to estimate the prevalence of presbycusis in an otologically normal population, i.e., without previous ear disease, exposure to noise, or potentially ototoxic substances, or familial hearing loss. METHODS: A total of 4290 subjects from 5 to 90 years old were included in the study. RESULTS: No statistically significant differences were found between right and left ear, nor between males and females, in any of the age groups. Presbycusis was detected over 60 years following the WHO classification; although the results vary depending on the classification used. Moderate hearing loss (≥ 41dB) was detected in the population over 72 years. None of the subjects had severe or profound hearing impairment. The prevalence of presbycusis increased with age, being 100% in individuals aged 80 years and older. The prevalence of presbycusis is highly variable depending on the pure-tone averaged frequencies and the classification system used; therefore, a common classification system should be used. CONCLUSIONS: An otologically normal population is needed to establish the prevalence of presbycusis as in non-screened populations it is the hearing level including all types of hearing loss that is measured, but not presbycusis itself.


Assuntos
Presbiacusia/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Espanha/epidemiologia , Adulto Jovem
7.
Acta otorrinolaringol. esp ; 70(4): 229-234, jul.-ago. 2019. tab, graf
Artigo em Inglês | IBECS | ID: ibc-185400

RESUMO

Objective: This is the first report dealing with immune-mediated inner ear disease (IMIED) hearing loss in a group of patients affected with autoimmune thyroid disease (AITD), whose treatment required corticosteroids, despite being treated with levothyroxine. Immunopathology linking the inner ear and the thyroid gland is also presented. Patients: A total of 220 patients were selected with sensorineural hearing loss (SNHL) of causes other than presbycusis. Audiometry was performed and pure tone average was calculated before and after treatment with corticosteroids. Results: Eighty-four (84) patients had SNHL of autoimmune origin, and 15 patients were diagnosed with AITD (Hashimoto's disease). Bilateral hearing loss was observed in 10 patients (66.5%). Sudden sensorineural hearing loss was the most frequent clinical form of presentation. Nine patients showed a hearing recovery greater than 10 dB after corticosteroid treatment. Conclusions: Acquired hypothyroidism is thought to affect hearing due to different mechanisms. Although specific hormonal therapy may improve peripheral or central auditory disorders associated with hypothyroidism, the presence of IMIED in AITD patients requires another approach. Altered immune regulatory mechanisms involving Treg cells and CD4+CD45RO cells have been suggested in patients with AITD and IMIED. In the present study, although all the patients with hypothyroidism and subclinical hypothyroidism were being treated with levothyroxine, immune-mediated hearing loss was observed. Therapy with corticosteroids could achieve hearing recovery. Since inner ear and thyroid gland share possible antigen targets, we highlight the existence of IMIED in AITD patients and the importance of implementing appropriate therapy with corticosteroids


Objetivo: Este es el primer trabajo que trata la hipoacusia por enfermedad inmune-mediada del oído interno (IMIED) en un grupo de pacientes afectados de tiroiditis autoinmune (AITD), cuyo tratamiento requirió corticosteroides, a pesar de haber sido tratados con levotiroxina. También se presenta la inmunopatología que vincula el oído interno y la glándula tiroides. Pacientes: Se seleccionó un total de 220 pacientes con hipoacusia neurosensorial (SNHL) por causas diferentes a presbiacusia. A todos los pacientes se les realizó una audiometría, calculándose la media de tonos puros antes y después del tratamiento con corticosteroides. Resultados: Ochenta y cuatro (84) pacientes tenían SNHL de origen autoinmune, y 15 pacientes fueron diagnosticados de AITD (Enfermedad de Hashimoto). Se observó hipoacusia bilateral en 10 pacientes (66,5%). La sordera súbita fue la forma de presentación clínica más frecuente. Nueve pacientes presentaron una recuperación auditiva superior a 10 dB tras el tratamiento con corticosteroides. Conclusiones: Se piensa que el hipotiroidismo adquirido afecta a la audición por diferentes mecanismos. Aunque la terapia hormonal específica puede mejorar los trastornos auditivos periféricos o centrales asociados al hipotiroidismo, la presencia de IMIED en los pacientes de AITD requiere otro abordaje. Se ha sugerido una alteración de los mecanismos reguladores de la respuesta inmune que implica a las células de Treg y a las células CD4+CD45RO en los pacientes con AITD e IMIED. En el presente estudio, a pesar de que todos los pacientes con hipotiroidismo e hipotiroidismo subclínico estaban siendo tratados con levotiroxina, se observó hipoacusia inmuno-mediada. La terapia con corticosteroides podría lograr una recuperación auditiva. Dado que el oído interno y la glándula tiroides comparten posibles antígenos diana, destacamos la existencia de IMIED en los pacientes de AITD, y la instauración de una terapia adecuada con corticosteroides


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Perda Auditiva Neurossensorial/etiologia , Tireoidite Autoimune/complicações , Especificidade de Anticorpos , Autoanticorpos , Autoantígenos/imunologia , Linfócitos T CD4-Positivos/imunologia , Doença de Hashimoto/complicações , Doença de Hashimoto/tratamento farmacológico , Doença de Hashimoto/imunologia , Perda Auditiva Neurossensorial , Perda Auditiva Neurossensorial/imunologia , Perda Auditiva Neurossensorial/prevenção & controle , Metilprednisolona/uso terapêutico , Transportadores de Sulfato/imunologia , Linfócitos T Reguladores/imunologia , Tireoidite Autoimune/tratamento farmacológico , Tiroxina/uso terapêutico
8.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-30107874

RESUMO

OBJECTIVE: This is the first report dealing with immune-mediated inner ear disease (IMIED) hearing loss in a group of patients affected with autoimmune thyroid disease (AITD), whose treatment required corticosteroids, despite being treated with levothyroxine. Immunopathology linking the inner ear and the thyroid gland is also presented. PATIENTS: A total of 220 patients were selected with sensorineural hearing loss (SNHL) of causes other than presbycusis. Audiometry was performed and pure tone average was calculated before and after treatment with corticosteroids. RESULTS: Eighty-four (84) patients had SNHL of autoimmune origin, and 15 patients were diagnosed with AITD (Hashimoto's disease). Bilateral hearing loss was observed in 10 patients (66.5%). Sudden sensorineural hearing loss was the most frequent clinical form of presentation. Nine patients showed a hearing recovery greater than 10dB after corticosteroid treatment. CONCLUSIONS: Acquired hypothyroidism is thought to affect hearing due to different mechanisms. Although specific hormonal therapy may improve peripheral or central auditory disorders associated with hypothyroidism, the presence of IMIED in AITD patients requires another approach. Altered immune regulatory mechanisms involving Treg cells and CD4+CD45RO cells have been suggested in patients with AITD and IMIED. In the present study, although all the patients with hypothyroidism and subclinical hypothyroidism were being treated with levothyroxine, immune-mediated hearing loss was observed. Therapy with corticosteroids could achieve hearing recovery. Since inner ear and thyroid gland share possible antigen targets, we highlight the existence of IMIED in AITD patients and the importance of implementing appropriate therapy with corticosteroids.


Assuntos
Perda Auditiva Neurossensorial/etiologia , Tireoidite Autoimune/complicações , Tiroxina/uso terapêutico , Adulto , Idoso , Especificidade de Anticorpos , Autoanticorpos/imunologia , Autoantígenos/imunologia , Linfócitos T CD4-Positivos/imunologia , Orelha Interna/imunologia , Feminino , Doença de Hashimoto/complicações , Doença de Hashimoto/tratamento farmacológico , Doença de Hashimoto/imunologia , Perda Auditiva Bilateral/etiologia , Perda Auditiva Bilateral/imunologia , Perda Auditiva Bilateral/prevenção & controle , Perda Auditiva Neurossensorial/imunologia , Perda Auditiva Neurossensorial/prevenção & controle , Perda Auditiva Unilateral/etiologia , Perda Auditiva Unilateral/imunologia , Perda Auditiva Unilateral/prevenção & controle , Humanos , Metilprednisolona/uso terapêutico , Pessoa de Meia-Idade , Transportadores de Sulfato/imunologia , Subpopulações de Linfócitos T/imunologia , Linfócitos T Reguladores/imunologia , Tireoidite Autoimune/tratamento farmacológico
9.
Acta otorrinolaringol. esp ; 67(3): 167-178, mayo-jun. 2016. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-151780

RESUMO

La esofagitis eosinofílica (EE) es una entidad clínico patológica reconocida recientemente y con una prevalencia que va en aumento desde su descripción inicial. Su diagnóstico representa un reto para diferentes especialistas, entre los que tiene un rol destacado el otorrinolaringólogo. La sospecha clínica ante un paciente que presenta episodios recidivantes de impactación de alimentos no punzantes o ante un niño con trastornos de la alimentación y antecedentes de atopia constituyen el primer signo de alerta de una posible EE. El objetivo de esta revisión persigue destacar el papel de la EE en el diagnóstico diferencial de los pacientes con trastornos de la deglución, así como dar a conocer las manifestaciones clínicas que deben alertar al otorrinolaringólogo para proseguir la realización de las pruebas encaminadas al diagnóstico de esta enfermedad. La esofagoscopia transnasal, realizada por el otorrinolaringólogo en consulta, ayudará a disminuir el número de casos infradiagnosticados. Dado que gran parte de los pacientes afectos de trastornos de la deglución van a ser evaluados por el otorrinolaringólogo, se hace imprescindible el reconocimiento de la EE, así como el manejo diagnóstico-terapéutico por un equipo multidisciplinar en el que se involucren, además del otorrinolaringólogo, pediatras, digestólogos, alergólogos y patólogos familiarizados con la enfermedad. La identificación del alimento responsable de la inflamación del esófago y su eliminación de la dieta es la clave del tratamiento de este desorden inmunomediado (AU)


Eosinophilic esophagitis (EE) is a recently recognised pathologic entity whose prevalence has risen significantly since it was first described. Its diagnosis represents a challenge for different medical specialties, among which ENT specialists play an important role. Clinical suspicion in a patient with recurrent food impaction or a child with eating disorders and history of hypersensitivity constitutes the first warning sign of a possible EE. The purpose of this review is to highlight EE as a possible differential diagnosis in patients with deglutition disorders and describe the possible clinical symptoms that should alert the ENT specialist to perform appropriate diagnostic tests and procedures. The transnasal esophagoscopy, performed in-office by the ENT, is ideal for reducing possible underdiagnosed cases. Given the fact that an ENT specialist will evaluate a great many patients with deglutition disorders, it is paramount for possible EE cases to be suspected and recognised so that a correct multidisciplinary approach involving not only ENT specialists but also paediatricians, gastroenterologists, allergologists and pathologists can be established. Identifying the dietary component responsible for the esophageal inflammation and removing that food from the patient's diet is the key in the treatment of this immune-mediated disease (AU)


Assuntos
Humanos , Esofagite/etiologia , Esofagite/patologia , Esofagite/fisiopatologia , Eosinofilia/etiologia , Eosinofilia/mortalidade , Eosinofilia/fisiopatologia , Esofagoscopia/métodos , Diagnóstico Diferencial , Incidência , Transtornos de Deglutição/diagnóstico , Transtornos da Alimentação e da Ingestão de Alimentos/complicações , Otolaringologia/instrumentação , Otolaringologia/métodos , Alergia e Imunologia/instrumentação , Doenças do Sistema Imunitário
10.
Acta otorrinolaringol. esp ; 67(1): 40-44, ene.-feb. 2016. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-148957

RESUMO

La detección precoz y el tratamiento adecuado de la hipoacusia es fundamental para minimizar las consecuencias de la pérdida auditiva. Además de la audiometría convencional (125-8.000 Hz), disponemos de la audiometría con extensión en altas frecuencias (9.000 - 20.000 Hz), que puede ser de gran utilidad en el diagnóstico precoz de hipoacusia en ciertas patologías, como es el efecto ototóxico de los tratamientos quimioterápicos, la exposición a ruido o el mal entendimiento del lenguaje, especialmente en ambientes ruidosos. Aquí se presentan 11 casos clínicos en los que la audiometría con extensión en altas frecuencias ha ayudado en la detección precoz de la hipoacusia en diversas patologías, a pesar de tener una audiometría normal en frecuencias convencionales. Se pretende así destacar la importancia de la exploración audiométrica en altas frecuencias, con el fin de que se convierta en una herramienta habitual en la exploración audiológica (AU)


Early detection and appropriate treatment of hearing loss are essential to minimise the consequences of hearing loss. In addition to conventional audiometry (125-8,000 Hz), extended high-frequency audiometry (9,000-20,000 Hz) is available. This type of audiometry may be useful in early diagnosis of hearing loss in certain conditions, such as the ototoxic effect of cisplatin-based treatment, noise exposure or oral misunderstanding, especially in noisy environments. Eleven examples are shown in which extended high-frequency audiometry has been useful in early detection of hearing loss, despite the subject having a normal conventional audiometry. The goal of the present paper was to highlight the importance of the extended high-frequency audiometry examination for it to become a standard tool in routine audiological examinations (AU)


Assuntos
Humanos , Masculino , Feminino , Adulto , Perda Auditiva/diagnóstico , Perda Auditiva/induzido quimicamente , Perda Auditiva/patologia , Audiometria , Audiometria/métodos , Diagnóstico Precoce , Presbiacusia/diagnóstico , Perda Auditiva Neurossensorial/diagnóstico , Perda Auditiva/etiologia , Zumbido/diagnóstico , Cisplatino/efeitos adversos
11.
Acta Otorrinolaringol Esp ; 67(3): 167-78, 2016.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-26452619

RESUMO

Eosinophilic esophagitis (EE) is a recently recognised pathologic entity whose prevalence has risen significantly since it was first described. Its diagnosis represents a challenge for different medical specialties, among which ENT specialists play an important role. Clinical suspicion in a patient with recurrent food impaction or a child with eating disorders and history of hypersensitivity constitutes the first warning sign of a possible EE. The purpose of this review is to highlight EE as a possible differential diagnosis in patients with deglutition disorders and describe the possible clinical symptoms that should alert the ENT specialist to perform appropriate diagnostic tests and procedures. The transnasal esophagoscopy, performed in-office by the ENT, is ideal for reducing possible underdiagnosed cases. Given the fact that an ENT specialist will evaluate a great many patients with deglutition disorders, it is paramount for possible EE cases to be suspected and recognised so that a correct multidisciplinary approach involving not only ENT specialists but also paediatricians, gastroenterologists, allergologists and pathologists can be established. Identifying the dietary component responsible for the esophageal inflammation and removing that food from the patient's diet is the key in the treatment of this immune-mediated disease.


Assuntos
Esofagite Eosinofílica/diagnóstico , Corticosteroides/uso terapêutico , Distribuição por Idade , Doenças Autoimunes/complicações , Terapia Combinada , Transtornos de Deglutição/etiologia , Diagnóstico Diferencial , Dilatação , Progressão da Doença , Esofagite Eosinofílica/epidemiologia , Esofagite Eosinofílica/etiologia , Esofagite Eosinofílica/fisiopatologia , Esofagite Eosinofílica/terapia , Estenose Esofágica/etiologia , Esofagoscopia , Hipersensibilidade Alimentar/complicações , Alimentos Formulados , Refluxo Gastroesofágico/complicações , Refluxo Gastroesofágico/diagnóstico , Gastroenteropatias/complicações , Humanos , Prevalência , Distribuição por Sexo
12.
Acta Otorrinolaringol Esp ; 67(1): 40-4, 2016.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-26025356

RESUMO

Early detection and appropriate treatment of hearing loss are essential to minimise the consequences of hearing loss. In addition to conventional audiometry (125-8,000 Hz), extended high-frequency audiometry (9,000-20,000 Hz) is available. This type of audiometry may be useful in early diagnosis of hearing loss in certain conditions, such as the ototoxic effect of cisplatin-based treatment, noise exposure or oral misunderstanding, especially in noisy environments. Eleven examples are shown in which extended high-frequency audiometry has been useful in early detection of hearing loss, despite the subject having a normal conventional audiometry. The goal of the present paper was to highlight the importance of the extended high-frequency audiometry examination for it to become a standard tool in routine audiological examinations.


Assuntos
Audiometria de Tons Puros , Limiar Auditivo , Cisplatino , Surdez , Diagnóstico Precoce , Perda Auditiva , Humanos
13.
Iran J Otorhinolaryngol ; 27(83): 475-9, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26788494

RESUMO

INTRODUCTION: Malignant tumors of the parotid gland account scarcely for 5% of all head and neck tumors. Most of these neoplasms have a high tendency for recurrence, local infiltration, perineural extension, and metastasis. Although uncommon, these malignant tumors require complex surgical treatment sometimes involving a total parotidectomy including a complete facial nerve resection. Severe functional and aesthetic facial defects are the result of a complete sacrifice or injury to isolated branches becoming an uncomfortable distress for patients and a major challenge for reconstructive surgeons. CASE REPORT: A case of a 54-year-old, systemically healthy male patient with a 4 month complaint of pain and swelling on the right side of the face is presented. The patient reported a rapid increase in the size of the lesion over the past 2 months. Imaging tests and histopathological analysis reported an adenoid cystic carcinoma. A complete parotidectomy was carried out with an intraoperative notice of facial nerve infiltration requiring a second intervention for nerve and defect reconstruction. A free ALT flap with vascularized nerve grafts was the surgical choice. A 6 month follow-up showed partial facial movement recovery and the facial defect mended. CONCLUSION: It is of critical importance to restore function to patients with facial nerve injury. Vascularized nerve grafts, in many clinical and experimental studies, have shown to result in better nerve regeneration than conventional non-vascularized nerve grafts. Nevertheless, there are factors that may affect the degree, speed and regeneration rate regarding the free fasciocutaneous flap. In complex head and neck defects following a total parotidectomy, the extended free fasciocutaneous ALT (anterior-lateral thigh) flap with a vascularized nerve graft is ideally suited for the reconstruction of the injured site. Donor-site morbidity is low and additional surgical time is minimal compared with the time of a single ALT flap transfer.

14.
Gerokomos (Madr., Ed. impr.) ; 25(2): 81-89, jun. 2014. graf, tab
Artigo em Espanhol | IBECS | ID: ibc-127310

RESUMO

Introducción: la curación de las heridas quirúrgicas en los pacientes sometidos a cirugía de cabeza y cuello es un factor esencial en el periodo postoperatorio. Una curación rápida y sin complicaciones mejora el estado general del paciente, limita la estancia hospitalaria y disminuye los costes médicos. En 2005 se introdujo en nuestro centro un protocolo para pacientes sometidos a cirugía de cabeza y cuello, consistente en la preparación de la herida quirúrgica mediante técnica de cura en ambiente húmedo (CAH). Material y métodos: se analizaron los datos de los pacientes sometidos a laringectomía total y laringectomía horizontal supraglótica entre 1995 y 2005 (grupo 1) y de 2005 a 2011 (grupo 2), con el fin de evaluar la estancia media hospitalaria y la formación de fístulas faringocutáneas antes y después de la introducción del protocolo de cura húmeda. Resultados: se analizaron 169 pacientes: 131 en el grupo 1 y 38 en el grupo 2. Más del 94% de los pacientes eran varones, con una media de edad de 60 años en el grupo 1 y de 68 años en el grupo 2. La formación de faringostoma fue significativamente mayor en el grupo 1 (42,9% frente a 26,1%), especialmente en pacientes que habían recibido radioterapia previa. La estancia hospitalaria media fue ligeramente superior en los pacientes del grupo 1. Conclusiones: la reducción de la estancia hospitalaria media y la disminución de la formación de faringostomas es fácilmente atribuible a la utilización del protocolo de CAH, lo que ahorra los costes sanitarios y mejora la calidad de vida del paciente


Introduction: Surgical wound healing is an essential factor for the head and neck patient in the postoperative period. A short and uncomplicated healing improves overall condition, and limits hospital stay and medical costs. A protocol for patients undergoing head and neck surgery consisting of preparation of the surgical wound as moist wound healing technique was introduced in our department in 2005. Material and Methods: Data from patients undergoing total laryngectomy and horizontal supraglottic laryngectomy were analyzed, from 1995 to 2005 (group 1), and from 2005 to 2011 (group 2), in order to assess the hospital stay average, and pharyngocutaneous fistula formation before and after the introduction of the protocol of moist wound healing (MWH). Results: 169 patients were analyzed: 131 from group 1 and 38 from group 2. More than 94% of patients were male, mean age 60 years in group 1 and 68 years in group 2. Pharyngostoma formation was significantly higher in group 1 (42.9% vs 26.1%), especially in patients who had received prior radiotherapy. Hospital stay average was slightly higher in patients from group 1. Conclusion: Reduction in hospital stay average and decreased formation of pharyngostoma is easily attributable to the use of the protocol of MWH, thus saving healthcare costs and improving the patient quality of life


Assuntos
Humanos , Deiscência da Ferida Operatória/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle , Técnicas de Fechamento de Ferimentos/enfermagem , Fístula Cutânea/prevenção & controle , Curativos Hidrocoloides , Curativos Oclusivos , Tempo de Internação/estatística & dados numéricos , Cabeça/cirurgia , Pescoço/cirurgia
15.
Acta Otorrinolaringol Esp ; 60(1): 43-8, 2009.
Artigo em Espanhol | MEDLINE | ID: mdl-19268129

RESUMO

INTRODUCTION: Many presbycusic patients have difficulty in understanding certain words. This could be justified because certain sounds in Spanish are more difficult to perceive, particularly the sounds with energy in the high frequencies. We propose to use a sentence as a tool to check this theory. MATERIALS AND METHOD: All the Spanish sounds were analyzed, measuring the degree of acoustic energy in all the frequencies. The conclusions drawn from the comparison of the results allowed the design of the tool that is proposed here. RESULTS: We established a gradient of perception difficulty, occlusive consonants being the least perceptible, followed by fricative, and finally all those segments with harmony and a clear formant structure. The Spanish sentence "Ana vio ese coche rojizo fino" is proposed as the tool for this study. This sentence has some as it comprises certain peculiarities that makes it particularly useful for this purpose. It will allow us to check whether understanding deteriorates as we move from beginning to end, helping evaluate the importance of high frequencies for intelligibility. CONCLUSIONS: A positive result could help in the design of amplification systems to improve speech intelligibility. In addition, the exploratory tool could allow neuro-acoustic exploration, useful in the central auditory pathology studies.


Assuntos
Audiometria da Fala , Acústica , Testes Auditivos/métodos , Humanos
16.
Acta otorrinolaringol. esp ; 60(1): 43-48, ene.-feb. 2009. ilus, tab
Artigo em Es | IBECS | ID: ibc-71542

RESUMO

Introducción. Muchos pacientes presbiacúsicos presentan dificultad para entender ciertas palabras, hecho que podría estar justificado porque determinados sonidos en español presentan una dificultad mayor de perceptibilidad, en concreto los de energía en altas frecuencias. Se propone utilizar una oración como herramienta para comprobar la hipótesis de partida. Material y método. Se analizaron todos los sonidos del español, midiendo el grado de energía acústica que presenta cada una de las frecuencias. Las conclusiones extraídas de la comparación de sus resultados permitieron el diseño de la herramienta que aquí se propone. Resultados. Se establece una gradación de dificultad perceptiva, por lo que se puede decir que las oclusivas aparecen como los sonidos menos perceptibles, seguido de las fricativas y, finalmente, todos los segmentos que presentan armonicidad y una estructura formántica definida. Como herramienta para la práctica clínica, se propone la frase española «Ana vio ese coche rojizo fino», frase que cumple una serie de particularidades que la hacen especialmente útil para tal fin. Esta oración permitirá comprobar si la comprensión se va deteriorando a medida que se avanza desde la primera a la última de sus secciones, y así poder suponer que la capacidad para detectar auditivamente la presencia de energía reforzada en las altas frecuencias es indispensable para la inteligibilidad. Conclusiones. Un resultado positivo podría tener como consecuencia el diseño de sistemas de amplificación que mejoren la inteligibilidad de la palabra. Además, el hecho de tener una herramienta exploratoria podría permitir la exploración neuroacústica, de utilidad en el estudio de la enfermedad auditiva


Introduction. Many presbycusic patients have difficulty in understanding certain words. This could be justified because certain sounds in Spanish are more difficult to perceive, particularly the sounds with energy in the high frequencies. We propose to use a sentence as a tool to check this theory. Materials and method. All the Spanish sounds were analyzed, measuring the degree of acoustic energy in all the frequencies. The conclusions drawn from the comparison of the results allowed the design of the tool that is proposed here. Results. We established a gradient of perception difficulty, occlusive consonants being the least perceptible, followed by fricative, and finally all those segments with harmony and a clear formant structure. The Spanish sentence «Ana vio ese coche rojizo fino» is proposed as the tool for this study. This sentence has some as it comprises certain peculiarities that makes it particularly useful for this purpose. It will allow us to check whether understanding deteriorates as we move from beginning to end, helping evaluate the importance of high frequencies for intelligibility. Conclusions. A positive result could help in the design of amplification systems to improve speech intelligibility. In addition, the exploratory tool could allow neuro-acoustic exploration, useful in the central auditory pathology studies


Assuntos
Humanos , Audiometria da Fala , Estimulação Acústica/métodos , Acústica da Fala , Testes Auditivos , Desenho de Equipamento/tendências
18.
Acta Otolaryngol ; 126(7): 679-84, 2006 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16803704

RESUMO

Syphilis is a well established cause of hearing loss. Sensorineural hearing loss may develop in the congenital or acquired form. The clinical course of the early acquired and late congenital forms are similar: sudden or rapidly progressive bilateral sensorineural hearing loss with mild vestibular symptoms. Cochleovestibular involvement in early acquired syphilis has been related to a basilar meningitis with lymphocytic infiltration of the labyrinth and VIIIth nerve. However, neurosyphilis and inner ear syphilis are not the same disease. Prompt diagnosis and treatment with corticosteroids and penicillin are mandatory to reduce the immune response and fibrosis of the labyrinth and the endolymphatic sac. Unfortunately, early acquired syphilis is frequently overlooked in the differential diagnosis of other forms of sensorineural hearing loss, particularly autoimmune inner ear disease. Given the increasing number of luetic infection cases, especially in immunocompromised patients, this condition should be considered in any sexually active patients affected by sudden hearing loss. Cases of inner ear syphilis are presented. Immunopathology of luetic inner ear infection is discussed and compared with immune disorders of the inner ear.


Assuntos
Doenças Autoimunes/diagnóstico , Otopatias/diagnóstico , Orelha Interna , Perda Auditiva Neurossensorial/etiologia , Sífilis/diagnóstico , Adolescente , Adulto , Idoso , Diagnóstico Diferencial , Técnicas de Diagnóstico Otológico , Otopatias/sangue , Otopatias/líquido cefalorraquidiano , Otopatias/imunologia , Feminino , Teste de Absorção do Anticorpo Treponêmico Fluorescente , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Sífilis/sangue , Sífilis/líquido cefalorraquidiano , Sífilis/imunologia , Sífilis Congênita/diagnóstico , Treponema pallidum/imunologia
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